Abstract

Objective: Oocyte cryopreservation would avoid legal and ethical problems associated with human embryo freezing and provide future fertility for women who are anticipating loss of gonadal function. However, the success rate of oocyte cryopreservation is still low. In nature, a variety of organisms including arctic frogs, tardigrades, and brine shrimp survive extreme dehydration conditions such as freezing and drought by accumulating sugars. The objective of this study was to examine whether sugars can be used as intracellular cryoprotectant for the cryopreservation of human oocytes.

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