Abstract

Novel therapies in spinal muscular atrophy (SMA) are changing outcomes. Focus has shifted to determining the optimal exercise prescription to maximize therapeutic effect. Outpatient therapy models are often limited to 1 session/week, which may not be adequate to make meaningful gains. Body-weight support harness systems (BWSS) are typically only available in medical facilities, limiting the time children can safely practice challenging activities. Our study aimed to understand the impact of daily in-home BWSS use to maximize therapeutic benefit of treated children with SMA.

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