Abstract
Hepatitis C virus is a single stranded RNA virus. It is a major cause of acute and chronic hepatitis. The mode of infection is usually through intravenous drug abuse or transfusion of infected blood or blood products. Health care workers are at risk for needle stick and other with high-risk sexual behavior is also considered a major risk factor for HCV infection. The incidence of new cases of acute HCV infection has sharply decreased in the United States during the past decade, but the prevalence remains high with approximately 2.7 million Americans infected with the virus. Chronic HCV infection progresses in roughly 75% of patients after acute infection by the virus. Chronic HCV infection is slowly progressive disease and results in severe morbidity in 20-30% of infected persons.
Highlights
Cutaneous manifestations of chronic HCV infection are found in 20-40% of patients and are often presented to the dermatologists for treatment
It is recognized that most extrahepatic manifestation of HCV infection are common in chronic kidney disease and can occur in 38% of patients [3]
Essential cryoglobulinemia or, is a lymphoproliferative disorder which leads to deposition of circulating immune complexes in small to medium sized blood vessels
Summary
Cutaneous manifestations of chronic HCV infection are found in 20-40% of patients and are often presented to the dermatologists for treatment. Dermatological diseases such as lichen planus, porphyria cutanea tarda, skin lymphoma, and vasculitis [3,4] In this mini-review will try to shed light on the skin manifestation of HCV infection in patients with chronic HCV infection. It is recognized that most extrahepatic manifestation of HCV infection are common in chronic kidney disease and can occur in 38% of patients [3]. Essential cryoglobulinemia or (type II mixed cryoglobulinemia), is a lymphoproliferative disorder which leads to deposition of circulating immune complexes in small to medium sized blood vessels This type of disorder is common with chronic. Chronic stimulation of the immune system by HCV infection can lead to progression of lymphoproliferative disorder. In this review will highlight the most common cutaneous manifestation of chronic hepatitis C infection with emphases on the common skin manifestations
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