Abstract
Abstract In the process of establishing a Biological Exposure Index (BEI), all significant routes of exposure to the chemical are considered, so that the expected quantity of the biological marker present in the specimen can be realistically estimated. Thus, BEIs are the measure of the amount of chemical absorbed into the body. The BEI is considered to be a bioequivalent to an atmospheric Threshold Limit Value (TLV). If the contribution to total body burden by dermal absorption is substantial, difficulties arise when the value of the BEI is to be reconciled with the value expected to be present due to inhalation exposure only at the TLV concentration. This apparent discrepancy becomes large with chemicals which readily penetrate the skin barrier and exhibit quick systemic absorption. The purpose of this paper is to focus attention on the contributory role of dermal absorption by reviewing pertinent data from the literature. These data readily illustrate why such discrepancies can occur. Industrial hygiene...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
