Abstract
BackgroundPrimary palmar and/or axillary focal hyperhidrosis is a frequent disorder characterized by excessive sweating beyond physiological needs, often leading to a substantial impairment of quality of life. Over the years several minimally invasive surgical treatments have been described, however results vary, and due to a lack of uniform surgical approach, technique and nomenclature are often difficult to compare. In this prospective study we sought to evaluate the safety and effectiveness of our standardized technique of single-port, one-stage bilateral thoracoscopic sympathicotomy.MethodsOn a prospective basis a hundred consecutive patients with severe or intolerable primary hyperhidrosis underwent one-stage bilateral single-port thoracoscopic sympathicotomy. Primary outcome was measured in pre- vs. post-operative Hyperhidrosis Disease Severity Scale scores. Location and extend of compensatory hyperhidrosis, and satisfaction with the procedure were registered.ResultsA significant reduction in mean Hyperhidrosis Disease Severity Scale score (3.69 ± 0.47 preoperatively vs. 1.06 ± 0.34 postoperatively) (p < 0.001) was observed. In 97 (97%) out of the 100 enrolled patients a >80% reduction in sweat production was achieved. Compensatory hyperhidrosis was seen in 27 patients (27%). It was rated as mild by 21 patients (78%) and as moderate by 6 (22%) of these patients. No severe compensatory hyperhidrosis was reported. Major complications, such as intraoperative bleeding, infections, and Horner’s syndrome were not observed.ConclusionsHighly selective sympathicotomy at well-defined levels with a one-stage bilateral single-port transaxillary thoracoscopic approach is a save procedure, with excellent and reproducible immediate results in the treatment of primary palmar and/or axillary hyperhidrosis.
Highlights
Primary palmar and/or axillary focal hyperhidrosis is a frequent disorder characterized by excessive sweating beyond physiological needs, often leading to a substantial impairment of quality of life
Severe palmar and/or axillary focal Primary hyperhidrosis (PHH) leads to feelings of shame and low self-esteem resulting in withdrawal from social activities, negatively affecting relational and professional development [2,3,4]
PHH is considered a benign disorder, it may have a deleterious impact on health related quality of life (HR-QoL)
Summary
Primary palmar and/or axillary focal hyperhidrosis is a frequent disorder characterized by excessive sweating beyond physiological needs, often leading to a substantial impairment of quality of life. PHH tends to begin around the mid second to early third decade of life, affects men and woman and has a focal and often symmetric character [1]. PHH is considered a benign disorder, it may have a deleterious impact on health related quality of life (HR-QoL) The reality that the latter has been underestimated until very recently is supported by the increasing reported prevalence in the literature, growing from 0.6% in 1977 to a recent 4.6% of the general population [1,5,6]. While acceptable results have been achieved with local surgery that aims at the eccrine-gland level [7], these strategies are quite invasive and by nature only able to relieve axillary PHH
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