Abstract
We report the development of a near real time single mode fiber-optic based polarizationsensitive optical coherence tomography (PSOCT) setup utilizing a swept source. The setuphas a polarization modulator (PM) and polarizer in a sample arm to serve as a polarizationstate generator and analyzer. Since only intensity information is used to retrieve thepolarization parameters of the sample, the problem of phase jitters present in the sweptsource is avoided. Further, the use of polarization elements after the sample armfiber makes the approach insensitive to the random birefringence of fibers. Theswept source based PSOCT (SS-PSOCT) setup was calibrated by carrying outmeasurements on a quarter-wave plate whose fast axis orientation was rotated from0° to360° in stepsof 10°. The setup has been used for imaging birefringence of mice tail tendon, thigh muscle exvivo and human nail fold in vivo.
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