Single-level Anterior Cervical discEctomy and Fusion has Lower Five-year Revisions than Posterior Cervical Foraminotomy in a Large National Cohort.

Abstract

Retrospective cohort study using the 2010-2020 MSpine PearlDiver administrative dataset. To compare perioperative adverse events and five-year revisions for single-level ACDF versus PCF. Cervical disc disease can often be treated surgically using single-level anterior cervical discectomy and fusion (ACDF) or posterior cervical foraminotomy (PCF). Prior studies have suggested that posterior approaches provide similar short-term outcomes as ACDF; however, posterior procedures may have an increased risk of revision surgery. The database was queried for patients undergoing elective single-level ACDF or PCF (excluding cases performed for myelopathy, trauma, neoplasm, and/or infection). Outcomes including specific complications, readmission and reoperations were assessed Multivariable logistic regression was used to ascertain odds ratios (OR) of 90-day adverse events controlling for age, sex, and co-morbidities. Kaplan-Meier survival analysis was performed to determine 5-year rates of cervical reoperation in the ACDF and PCF cohorts. A total of 31,953 patients treated by ACDF (29,958, 93.76%) or PCF (1,995, 6.24%) were identified. Multivariable analysis, controlling for age, sex, and comorbidities, demonstrated that PCF was associated with a significantly greater odds of aggregated serious adverse events (OR 2.17, P<0.001), wound dehiscence (OR 5.89, P<0.001), surgical site infection (OR 3.66, P<0.001), and pulmonary embolism (OR 1.72, P=0.04). However, PCF was associated with significantly lower odds of readmission (OR 0.32, P<0.001), dysphagia (OR 0.44, P<0.001), and pneumonia (OR 0.50, P=0.004). At five years, PCF cases had a significantly higher cumulative revision rate compared to ACDF cases (19.0% vs. 14.8%, P<0.001). he current study is the largest to date to compare short-term adverse events and five-year revision rates between single-level ACDF and PCF for non-myelopathy elective cases. Perioperative adverse events differed by procedure, and it was notable that the incidence of cumulative revisions was higher for PCF. These findings can be used in decision making when there is clinical equipoise between ACDF and PCF.