Abstract
Single-cell RNA sequencing is a method for transcriptome profiling at the single-cell level, and is a hotspot technology in the field of biological research currently. Compared with the common high-throughput RNA sequencing, single-cell RNA sequencing can distinguish the biological differences between single cells, and identify rare cell populations and subpopulations. This review mainly describes the single-cell RNA sequencing method, summarizes current application of this technique in the field of dermatology, and discusses limitations and prospects of this technique. Key words: Sequence analysis, RNA; Single-cell RNA sequencing; High-throughput RNA sequencing; Dermatology; Genetic heterogeneity
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