This Letter reports on the experimental observation of a topologically protected edge state and exceptional point in an open and non-Hermitian (lossy) acoustic system. Although the theoretical underpinning is generic to wave physics, the simulations and experiments are performed for an acoustic system. It has nontrivial topological properties that can be characterized by the Chern number provided that a synthetic dimension is introduced. Unidirectional reflectionless propagation, a hallmark of exceptional points, is unambiguously observed in both simulations and experiments.

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