Abstract
Abstract A method is described for the simultaneous automated fluorometric estimation of noradrenaline and dopamine in brain extracts. It is based on a slight modification of the automated method for dopamine published recently. Interference of noradrenaline in the estimation of dopamine, and vice versa, is low (0.8 and 1.4%, respectively). Interferences of other catechols and related compounds have also been studied. Samples can be processed at a rate of 30 per hour, and the limit of sensitivity for both amines is about 2 ng/ml of brain extract.
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