Abstract
Simulation Studies for the Effects of Particle Size and Blade Rake Angle on Particle Mixing
Highlights
Solid particle mixing is an important unit operation in process industry. In pharmaceutical industry it is of particular importance because the Active Pharmaceutical Ingredient (API) has to be properly mixed which is normally in the quantity of few milligrams in the final dosage form, and if not mixed properly can have no or severe therapeutic effects depending on API quantity
Particle mixing is usually perceived as a simple unit operation because it does not involve any high-tech and complicated equipment but this operation is still under spotlight of latest research to understand complexity of the underlying physical phenomena
Mixing of solid particles depends on several parameters like nature of the material of the particles, their size, shape, number, and loading/unloading profile
Summary
Solid particle mixing is an important unit operation in process industry. In pharmaceutical industry it is of particular importance because the Active Pharmaceutical Ingredient (API) has to be properly mixed which is normally in the quantity of few milligrams in the final dosage form, and if not mixed properly can have no or severe therapeutic effects depending on API quantity. Simulation Studies for the Effects of Particle Size and Blade Rake Angle on Particle Mixing Solid particle mixing is an important unit operation in process industry.
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