Abstract

In concern of cervical cancer through the various screening and health care programmes running in Asian and Western countries, it was established that the prevalence and mortality has declined tremendously. However cervical cancer is still considered as one of the fetal and common cancer in females, followed by breast cancer and lung cancer in India. In the present study, blood samples of confirmed cervical cancer patients through biopsy examination were collected and subjected for genomic DNA isolation. Isolated DNA samples were amplified for detection of NAT-2 gene, subsequently gene polymorphism was detected using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. We observed that NAT-2 gene polymorphism was significantly associated with cervical cancer risk.

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