Abstract

This Practice Point commentary discusses the study by Stief and colleagues, and the relationship between lower urinary tract symptoms (LUTS), erectile dysfunction (ED), and benign prostatic hyperplasia (BPH). This randomized, placebo-controlled study analyzed the effects of the phosphodiesterase type 5 inhibitor vardenafil (a treatment for ED) on LUTS related to BPH. Significant improvements in LUTS were observed in patients in the vardenafil group compared with those in the placebo group, and improvements in erectile function and quality of life were reported in both groups. The treatment was well tolerated. The design of this study and the characteristics of the selected study populations were not typical for a BPH study. Consequently, while this study demonstrates that vardenafil is a promising treatment for symptoms secondary to BPH, including LUTS and ED, further studies are needed before phosphodiesterase type 5 inhibitors become a treatment for LUTS associated with BPH.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.