Should renal ultrasonography be done routinely in children with first urinary tract infection?

Abstract

To reassess the impact of renal ultrasonography on the care of children with first febrile urinary tract infection (UTI) we conducted a computer search and review of medical records of (1) all children who were admitted to our hospital with first febrile urinary tract infection and underwent renal ultrasonography during a 25-month period beginning February 1, 1995, (2) all children diagnosed by ultrasound to have hydronephrosis during the same time period. Of a total of 124 patients with UTI, renal ultrasound appeared normal or showed evidence of acute pyelonephritis in 105 (84.7%), and in another nine (7.2%) it showed only minor findings. In 10 children (8.1%) ultrasound showed hydronephrosis and/or hydroureter. In eight of the latter 10, voiding cystourethrography showed vesicoureteral reflux; in one, posterior urethral valves; and in one, who had a unilateral nonobstructed dilatated system, cystography appeared normal. Except for the last patient, who was given prophylactic antibiotics and continued to have urinary tract infections, in no other case did ultrasound alone have any impact on the patient's management. Four children with both abnormal-appearing renal ultrasound and voiding cystourethrography required surgical intervention. One hundred of the 124 children had a voiding cystourethrogram. In 38 children it detected vesicoureteral reflux and, in another two, bladder abnormalities. Thirty-five of those with abnormal-appearing cystogram but without an indication for surgery were given prophylactic antibiotics. During the same 25-month period, 63 children without urinary tract infection were diagnosed by ultrasound with hydronephrosis. In 45 of them (71.4%) the urologic abnormality had already been detected by prenatal ultrasound. Fourteen of these 45 children (31.1%) required surgery, all for congenital anomalies related to obstructive uropathy. We conclude that routine renal ultrasonography in children with first urinary tract infection has negligible influence on their clinical management. This seems to be due to the recent widespread use, in industrialized countries, of maternal-fetal ultrasonography, which already detects a significant number of children with congenital obstructive uropathy prenatally. On the other hand imaging of the lower urinary tract is of high yield and contributes significantly to patient care. Therefore, whereas imaging of the lower urinary tract should continue to be done routinely in children with first urinary tract infection, renal ultrasound may be reserved for more select cases.