Should pharmaceutical scientists use liposomes or micelles as a means for drug delivery?

Abstract

Nanotechnology is the manipulation of matter on a near-atomic scale to produce structures, machines, and devices. Nanotechnology is being used as a method to deliver drugs to combat cancer due to current, artificial systems producing harmful side effects. In this, two main systems stand out: liposomes and micelles. This paper compares the two systems to decide whether one system is more capable and should currently be used in drug deliveries. This paper will look at the structure of liposomes and micelles, clinical studies, and issues that have been noted. It was found that liposomes have a higher carrying capacity and can carry multiple types of drugs. In clinical trials, liposomes were found to be just as effective as current systems. However, they are known to have premature drug releases as well as being difficult to load. Micelles were found to be smaller, making them easier to enter the body. They are also easier to manufacture. In clinical studies, they were found to be just as effective as current systems. However, micelles are not as flexible, have a smaller volume, and much less stable than liposomes. Through compiling the advantages and disadvantages of both of these systems, it was found that overall, liposomes were a better system for drug delivery.