Abstract
A one-step radiolabeling procedure of highly magnetic particles with the therapeutic β-emitter rhenium-188 (188Re) has been developed. Magnetic targeted carriers (MTCs) are composites of metallic iron and activated carbon that can be labeled in the presence of the reducing agent SnCl2. As MTCs are effectively targeted to solid tumors, the 188Re-MTC complex has the potential to deliver therapeutically relevant doses of radiation to tumors while minimizing radiation exposure to surrounding tissues or organs.
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