Abstract

Section I: The Morphology and Pathogenesis of Acute Lung Injury.- 1 Fluid Flux Across the Microvascular Endothelium.- 2 The Morphology of the Adult Respiratory Distress Syndrome.- 3 Mediators in Acute Lung Injury: The Whole Body Inflammatory Response Hypothesis.- 4 Intravascular Microaggregates and Pulmonary Embolization in Shock and Surgery.- Section II: Pathophysiology of Septic Shock and the Adult Respiratory Distress Syndrome.- 5 Biochemical Changes in Patients at Risk from the Adult Respiratory Distress Syndrome: Does the Pancreas Play a Role?.- 6 Changing Haemodynamic Concepts in Human Septic Shock.- 7 Oxygen Delivery and Consumption in the Critically Ill: Their Relation to the Development of Multiple Organ Failure.- 8 Right Ventricular Performance and Positive End-Expiratory Pressure Ventilation.- Section III: Some Aspects of Ventilatory Support.- 9 The Physiological Basis of Ventilatory and Respiratory Support.- 10 The Arterial-Alveolar Nitrogen Difference for the Assessment of Ventilation-Perfusion Mismatch.- 11 High-frequency Ventilation: A Step Towards Compliance-Independent Ventilation.- 12 Extracorporeal Support in Acute Respiratory Failure.- Section IV: Some Aspects of Cardiovascular Support.- 13 The Role of Fluid Replacement in Acute Endotoxin Shock.- 14 Optimal Use of Vasoactive Agents in Septic Shock.- 15 Mechanical Assistance in the Treatment of Shock.- Section V: The Diagnosis and Prognosis of the Adult Respiratory Distress Syndrome.- 16 Prognosis in the Intensive Care Unit: General Principles and Application to Patients with the Adult Respiratory Distress Syndrome.- 17 Adult Respiratory Distress Syndrome: A Scoring System for the Estimation of the Gravity of Pulmonary Disease and Comparison of Patient Populations.- 18 The Clinical Presentation and Diagnosis of the Adult Respiratory Distress Syndrome.

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