Abstract
We describe the fabrication of porous foams with shape memory triggering at body temperature. Employing a modified porogen-leaching technique, functionalized poly(ε-caprolactone) (PCL) and poly(ethylene glycol) (PEG) macromers are crosslinked via thiol-ene chemistry to generate highly porous foam scaffolds with shape memory capacity. The temperature at which shape change of these scaffolds occurs under hydrated conditions can be tuned both through control of the chemical composition and through deformation temperature during mechanical programming of the scaffolds. Uniquely, the foams exhibit reversible actuation in compression, which has not previously been demonstrated for foams. Our results indicate that PCL-PEG shape memory foams have potential as programmable scaffolds for tissue engineering, regenerative medicine, and the study of cell mechanobiology.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
