Abstract

A cytotoxic sesquiterpene (1) with a tricyclo [6.3.1.0.2,5] dodecane skeleton has been isolated from the extract of a New Zealand Eurypon sp. of sponge. Two derivatives, (2) and (3), of this sesquiterpene have also been isolated, probably as artefacts arising during the isolation procedure. The structure of a spiro sesquiterpene (4), also obtained from the sponge extract, has been determined. Previously published n.m.r. assignments for β-caryophyllene alcohol (5) have been revised.

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