Abstract
Aim: Serum proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with low-density lipoprotein (LDL) catabolism and is implicated in cardiovascular disease (CVD). A Mediterranean diet is a dietary pattern associated with a reduction of diabetes and CVD incidence. Aim of the study was to assess possible differences in serum PCSK9 levels between otherwise healthy drug-naïve obese subjects (n=30, age 42 ± 10y) and healthy individuals with normal body weight (n=25, age 36 ± 6y), as well as possible correlation between PCSK9 levels and a Mediterranean diet score.
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