Abstract
Japanese Encephalitis (JE), a vector-borne zoonotic viral disease, is mostly prevalent in Asian countries. The objective of this study was to investigate the occurence of JE virus (JEV) among pigs in East Sumba, Indonesia. Blood samples (n=52) were randomly collected from 52 apparantly healthy pigs where pig population was high in East Sumba. The samples were subjected for seroprevalence study for the presence of antibodies against JEV using competitive enzyme linked immunosorbent assay (C-ELISA). Results showed that 53% (n=28/52) blood samples from the pigs contained antibodies against JEV. This finding is suggestive that the JEV is circulating among pig population in East Sumba, Indonesia. The data may help in designing control strategies of the JEV in the East Sumba, Indonesia.
Highlights
Japanese Encephalitis (JE), a viral disease caused by Japanese Encephalitis Virus (JEV), is a vector-borne zoonotic disease occuring mostly in Southeast Asia, East Asia, South Asia, and the Pacific (Shimojima et al, 2011)
A total of 52 serum samples from 52 pigs were tested by competitive enzyme-linked immunosorbent assay (C-ELISA), of which 53% (n=28/52) serum samples were found to be seropositive for antibodies against JEV (Figure 1)
The houses of the owners located adjacent to rice fields influenced the occurrence of JE, as the rice fields are known to be a source of Culex mosquito breeding
Summary
Japanese Encephalitis (JE), a viral disease caused by Japanese Encephalitis Virus (JEV), is a vector-borne zoonotic disease occuring mostly in Southeast Asia, East Asia, South Asia, and the Pacific (Shimojima et al, 2011). About 3 billion people live in the countries where JEV is endemic, and the annual incidence of the disease is estimated as 30,000-50,000 cases (Saxena, 2008). The JE has considerable fluctuations in estimates of its global impact (WHO, 2008). Pigs play an important role as major amplifying host of JEV exerting potential health risk to human (Ritchie et al, 2007; Yamanaka et al, 2010). Culex mosquitoes may act as the amplifying intermediate host of JEV (Hurk et al, 2008). The clinical manifestations of JE in human include febrile illness, aseptic meningitis or encephalitis which manifests sensorium, seizures and focal neurological deficit and acute flaccid paralysis (Liu et al, 2010)
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