Abstract

Low functioning of the N -methyl-D-aspartate (NMDA) receptor has been hypothesized for schizophrenia. Clinical evidence for this hypothesis includes psychotic effects of phencyclidine, which acts at the NMDA receptor, and preliminary positive findings of treatment with d-serine, a co-agonist at the NMDA receptor (JW Psychiatry Sep 3 2010). In mice, …

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