Abstract

Private companies have recently started to sell epigenetic tests to the public online, most of them without supervision by a physician. While the ethical and legal implications of direct-to-consumer genetic testing have received considerable attention over the past decades, other direct-to-consumer ‘omic’ tests have largely escaped scrutiny. Direct-to-consumer epigenetic tests have the potential to reveal sensitive information about individuals, such as disease risk and exposure history. Yet regulation lags behind purely genetics-based tests. In this Comment article, the authors discuss the salient ethical and legal considerations of direct-to-consumer epigenetic tests.

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