Abstract
High efficiency photosensitizers for corneal neovascularization therapy are of importance because of their great advantages such as little adverse side effect and selective treatment. However, to develop high performance photosensitizer to cure the corneal disease remain challenging. In this work, a novel amphiphilic boron dipyrromethene (BODIPY) derivative (BDPY) was synthesized and it could self-assembly into nanoparticles in aqueous solution. These BDPY nanoparticles exhibited good photodynamic therapy effect on the corneal angiogenesis. The extended conjugation structure of BDPY lead to red-shift absorption and generated singlet oxygen upon red light irradiation. Our work might provide an interesting and valuable platform to design novel medicines for the new vessels of corneal therapy application.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Colloids and Surfaces A: Physicochemical and Engineering Aspects
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
