Abstract
Infective endocarditis (IE) is a serious infection of the heart with a high morbidity and mortality. In the case of native valve endocarditis (NVE), the infection is often associated with cardiac abnormalities in patients. Viridans streptococci from the oral cavity1 account for over 40% of all IE cases. These bacteria can transiently be present in the bloodstream after e.g. dental procedures, flossing or brushing of the teeth. They are able to adhere to nonbacterial thrombic vegetations, platelet-fibrin meshworks present at lesions of the endocard or the heart valves. Colonization promotes a further accretion of platelets and fibrin on the vegetation. The onset of IE is then caused by a rapid multiplication of the bacteria inside the vegetation, in which they are shielded from host cellular defenses.KeywordsInfective EndocarditisSelection SystemBroad Host RangeSelection CassetteNative Valve EndocarditisThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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