Abstract
Background Rising hypertension prevalence, coupled with increasing overweight and obesity rates, has been observed in Yi people. Moreover, the growing blood pressure level among Yi people was mostly attributable to the continuous increase of body mass index (BMI). However, little is known about the trend of association between them. Methods Consequently, we investigated the impact of overweight/obesity on hypertension over three periods (1996, 2007-2008, 2015) using data from Yi Migrant Study (n = 8749). The Yi Migrant Study incorporated three successive cross-sectional studies which were implemented by the same team with consistent protocols. Results Compared with period 1 (1996), the influence of overweight/obesity on hypertension risk significantly increased in period 2 (2007-2008) and period 3 (2015); relative excess risk due to interaction (RERI) was 1.59 (95% CI: 0.12, 3.05) and 1.41 (95% CI: 0.30, 2.78), respectively. Meanwhile, the overweight/obese population in period 3 did not show hypertension risk higher than that in period 2 (RERI = 0.15; 95% CI: −0.76, 1.07). Additionally, we observed a continuously growing trend of hypertension risk among normal weight Yi people. Conclusions During the past two decades, there was a significant increase in the association between overweight/obesity and hypertension in Yi people, whereas the increasing trend has leveled off in more recent years. These findings suggest that overweight/obesity and hypertension are becoming more epidemic comorbidity over time. Interventions to prevent hypertension should focus not only on the overweight/obese population, but also on those with normal weight.
Highlights
Hypertension, known as raised blood pressure (BP), is one of the most common medical disorders and the strongest modifiable risk factors of cardiovascular disease, which is a leading cause of death [1, 2]
We evaluated whether the associations between overweight/obesity and hypertension among Yi people varied by time periods both on multiplicative and additive scales. e P-values of the cross-product interaction term in the multiple logistic models were used to test for the multiplicative interaction [21]. e additive interaction was measured with relative excess risk due to interaction (RERI), using the following equation [21, 22]: RERI RR11 − RR10 − RR01 + 1
We found a significant increase in the association between overweight/obesity and hypertension from 1996 to 2015 among Yi people
Summary
Hypertension, known as raised blood pressure (BP), is one of the most common medical disorders and the strongest modifiable risk factors of cardiovascular disease, which is a leading cause of death [1, 2]. During the past several decades, we witnessed an enormously increasing trend of hypertension prevalence worldwide [3,4,5]. As one of the most common risk factors for hypertension, excess weight gain can be the cause of 78% of primary hypertension in men and 65% in women [8]. Rising hypertension prevalence, coupled with increasing overweight and obesity rates, has been observed in Yi people. The growing blood pressure level among Yi people was mostly attributable to the continuous increase of body mass index (BMI). We observed a continuously growing trend of hypertension risk among normal weight Yi people. During the past two decades, there was a significant increase in the association between overweight/obesity and hypertension in Yi people, whereas the increasing trend has leveled off in more recent years. Interventions to prevent hypertension should focus on the overweight/obese population, and on those with normal weight
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
