Abstract
Piomelli et al.1 have presented an extensive experience in comparison of free erythrocyte porphyrin (FEP) levels with blood lead concentrations. Their finding that an FEP ≥ 250µg/100 ml RBC was invariably associated with a blood lead concentration ≥ 6Oµg/100 ml is consistent with data obtained in our laboratory2 using a somewhat different microfluorometric method for FEP determination.3 We must, however, take issue with the conclusion of Piomelli et al.1 that only FEP levels above 250µg/100 ml RBC should be considered "positive."
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