Abstract

Tuberculosis is a disease mainly caused by Mycobacterium tuberculosis. It is estimated that one-third of the world's population is infected with tuberculosis bacillus and two million people will develop an active disease per year. The increasing prevalence of the disease is due to the emergence of multidrug-resistant strains as well to the HIV pandemic which provides a large reservoir of highly susceptible individuals [1]. Since no anti-tuberculosis drugs have been introduced in the past 30 years, there is an urgent need for new effective anti-mycobacterial agents to circumvent new drug resistance cases. In this instance, the plant kingdom is undoubtedly a valuable source for new potential anti-tuberculosis agents to be explored [2].

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