Abstract
1. A Heart Attack: David Allison's terrifying experience 2. The Revolution of 1912: James Herrick insists that heart attacks are caused by clots and are survivable 3. Creating the Platform: Jay McLean, Werner Forssman and John Gibbon make the discoveries that make treatment possible 4. Groping in the Dark: Primitive attempts at coronary surgery are made and Mason Sones invents the diagnostic test that makes bypass surgery possible 5. Accidents and Innovations: How bypass surgery began, how Rene Favaloro made it matter, and how three big clinical trials tested what it could do 6. Surgeons: John Kirklin, Paul Taylor, and what it takes to be a heart surgeon 7. Smart Operators: Wesley Sterman and Charles Taylor put engineering and entrepreneurship at the service of surgery, and vice versa 8. A Momentous Decision: Lewis Hollander decides to have beating-heart surgery 9. A Balloon on a Snake: Andreas Gruentzig invents angioplasty and flames out in a storm over Georgia 10. The Interventionalist as Entrepreneur: John Simpson invents a better catheter 11. Trials and Errors: BARI and EAST, two big, well-conducted clinical trials that might not have warranted the multi-million dollar investment of taxpayer dollars 12. Interventional Cardiology Expands: Julio Palmaz invents the coronary stent 13. How Healing Can Harm: The hunt for the molecular causes of heart attacks 14. What Shall We Make of All This?: A critical summation APPENDIX A: DESIGNING AND MOUNTING CLINICAL TRIALS APPENDIX B: WHAT PATIENTS NEED TO KNOW
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