Abstract
Currently there is no validated serum creatinine based eGFR equation available to accurately measure renal function in pregnancy, partly because pregnancy related weight and body surface area changes are not representative of an increase in serum creatinine production. In order to perform accurate renal function measurements in pregnancy, 24-hour urine collections are required to measure the 24-hour creatinine clearance rate. The purpose of this study is to assess the accuracy of the non-weight based, serum creatinine based NANRA equation for calculating eGFR in the setting of pregnancy, as well as assessing the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, and a CKD-EPI adjusted Body Surface Area (BSA) equation.
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