Abstract
Sarcoidosis involves abnormal collections of inflammatory cells (granulomas) which may form as nodules in multiple organs. 90% of affected patients have respiratory tract abnormalities. We present a 61-year-old male with sarcoidosis who was admitted for respiratory distress. Fibrosing mediastinitis was seen in the chest computograph. Management was conservative and included steroids, antibiotics, and oxygen therapy. Sarcoidosis and fibrosing mediastinitis are rare. Fibrosing mediastinitis is more commonly seen with histoplasmosis. We explore the clinical similarities between histoplasmosis and sarcoidosis. We also explore the potential cause and effect relationship and workup for each disease entity.
Highlights
Sarcoidosis involves abnormal collections of inflammatory cells, which may form as nodules in multiple organs
Sarcoidosis and histoplasmosis have a striking resemblance in terms of clinical presentation
The radiographic finding of fibrosing mediastinitis is commonly associated with histoplasmosis [3]
Summary
Sarcoidosis involves abnormal collections of inflammatory cells (granulomas), which may form as nodules in multiple organs It is considered a diagnosis of exclusion and most commonly presents with respiratory symptoms. Misdiagnosing one for the other and starting the incorrect treatment plan could cause significant morbidity In this case, we present a male patient diagnosed with sarcoidosis. History was obtained by personal interview and clinic and hospital medical records His radiographic finding of fibrosing mediastinitis is rare in sarcoidosis and more commonly seen with histoplasmosis. We review this case to make clinicians aware of the striking resemblance between these two entities and the workup that is recommended to accurately diagnose each disease
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