Abstract

Sarcoid neuropathy has a broader spectrum of clinical features than previously expected. It is typically characterized by multiple mononeuropathy but often shows a polyneuropathy pattern, making it difficult to be differentiated from other neuropathies. In the diagnostic process, several clinical features, including laterality and proximal-predominance of symptoms at extremities, sensory deficits in the territory of the branch of the peripheral nerve trunk, and positive neuropathic sensory symptoms typically accompanied by pain, could be the cues to evaluate the probability of sarcoid neuropathy. Axonal disturbance with a patchy distribution is a rule in nerve conduction studies; however, abnormalities suggestive of demyelination are also seen, imitating the clinical picture of chronic inflammatory demyelinating polyneuropathy.

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