Abstract
Abstract The Sandmeyer reaction is a two‐step synthesis of aryl halides or cyanides from primary aryl amines involving the formation of diazonium salts of the corresponding amines with nitrous, acid and the transformation of diazo intermediates into aryl halides or cyanides with cuprous halides or cyanide. The combination of the alkali halide and cuprous halide is known as the Sandmeyer reagent. It has also indicated that the halo group is introduced into the aromatic ring originates from cuprous halide instead of the diazonium halide. In addition, the halogen exchange has also been observed in the Sandmeyer reaction. Several procedures have been applied to enhance the yield of final outcome. Overall, this reaction usually gives less than a quantitative yield of aryl halide due to the formation of some side products.
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