Abstract
We report the changes in salivary pattern of normal pregnant women in each trimester qualitatively and quantitatively. FTIR spectroscopic technique has been successfully applied to analyze the saliva samples of various age groups from18 to 25 and 25 to 35. The role of FTIR spectroscopy in the analysis of saliva of normal pregnant women of 1 st , 2 nd and 3 rd trimester of various age groups are clearly demonstrated both qualitatively and quantitatively. Among the three trimesters, the vibrational peaks of the progesterone increased in the 1 st trimester: whereas, in the 2 nd trimester there was a decrease: In 3 rd trimester there was a further decrease. Similarly, in the case of normal pregnant women of age between 25 to 35 has a greater absorption value than the normal pregnant women of age 18 to 25. This may be attributed to the salivary IgA and IgM concentrations higher in ageing people. It is concluded that FTIR salivary signature may be applied to indicate different stage of pregnancy of different age group.
Highlights
The use of infrared spectroscopy for biomedical and genitourinary systems
Fourier Transform Infrared (FTIR) Spectroscopy is present work reports the changes that occur during a non-invasive, reagent free diagnostic tool in the normal pregnancy in each trimester of various age groups analysis of biological fluids
FTIR spectroscopy as a bio-diagonostic tool to predict changes occur during pregnancy of 1st, 2nd, ISSN: 0974- 6846
Summary
The use of infrared spectroscopy for biomedical and genitourinary systems. Local physical changes occur applications has increased tremendously in the recent in different parts of the body, including the oral cavity. Fourier Transform Infrared (FTIR) Spectroscopy is present work reports the changes that occur during a non-invasive, reagent free diagnostic tool in the normal pregnancy in each trimester of various age groups analysis of biological fluids. IR absorption employed in the qualitative and quantitative investigation patterns provide the basis to distinguish among the of biological fluids like saliva, blood, serum, urine etc. In constituents and to separately quantify them. Addition, these techniques provide molecular-level IR- based analytical methods require very small sample information allowing investigation of functional groups, volumes (typically microlitres), show good precision over bonding types and molecular conformations. Spectral the entire physiological range, and are well suited for bands in vibrational spectra provide direct information automation
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