Abstract

In a period of two years a series of three-home studies involving 26 families in Arizona was conducted to further evaluate the safety of the dichlorvos (DDVP)- containing insecticide strip. Physical examination, hematologic and clinical chemistry measurements, blood cholinesterase assays, and analysis of air and food for dichlorvos were carried out. Exposures were designed to be exaggerated in that strips were used throughout the homes (averaging 7 to 11 per home) and replaced with fresh ones, either every three months for one year or monthly for six months. Throughout the studies, all examinations and measurements revealed no adverse effect on health. The red cell cholinesterase activity also remained unaffected. A slight plasma cholinesterase depression of no toxicological importance was observed in the study where the strips were replaced monthly over six months. In homes containing 8 to 18 strips, maximum air and food concentrations of dichlorvos averaged approximately 0.13 mg/cu m and 0.12 ppm, respe...

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