Abstract
Individuals with 22q11.2 deletion syndrome (22q11DS), a genetic high-risk (25%) model of schizophrenia, show on average a modest decline in IQ between 8 and 24 years. This IQ pattern may represent a developmental phenotype that is specific to 22q11DS. To further characterize this, we constructed a 22q11DS-specific normative chart for cognitive development.
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