Abstract
An early decrease in 86Rb uptake was found in lenses of galactose-fed rats. Dissections in normal rat lenses showed that 86Rb acoumulation occurred in areas closer to the lens epithelium. The decreased uptake in lenses of galactosemic rats occurred in all lens areas; however, these lenses recovered their ability to accumulate 86Rb following galactose withdrawal from the diet. High dulcitol (galactitol) levels were found in lenses of galactose-fed rats. Dulcitol accumulations in the lens suggested a possible inhibitory role of this metabolite on the concentrating mechanisms of cations and amino acids in the lens during the development of galactose cataract in rats.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
