Abstract
Rosacea is a chronic inflammatory disease. Its frequency is higher in pale-skinned people and women over 30 years. Disease mechanisms include: abnormalities in innate immunity, inflammatory reactions to microorganisms, ultraviolet radiation damage, and vascular dysfunction. There are four clinical subtypes: erythematotelangiectatic, pustular papules, phymatous and ocular rosacea. Patients may present one or more characteristics of each subtypes. Injuries are classically located in midface area. Extreme temperatures, UV radiation, hot beberages, spicy foods, alcohol, exercise, topical irritants, psychological symptoms and drugs are associated to exacerbations. Clinical evaluation of the patient is usually enough for diagnosis. Nonpharmacologic interventions are essential for treatment. These include avoiding use of cosmetic, and triggers, skin care, and broad-spectrum sun protection. Patients with no response to general measures can respond to pharmacological agents. Topical metronidazole and azelaic acid are considered
 first-line treatments in mild to moderate disease. Oral tetracycline, have been used for many years for the treatment of papulopustular rosacea. Isotretinoin is useful in refractory disease. Treatment must be continous to maintain the response.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
