Abstract
a c s t e t t Rosai-Dorfman disease (RDD), first described in 1969, also known as sinus histiocytosis with massive lymphadenopathy, is an uncommon, benign histiocytic disorder of unknown etiology. It predominantly affects children and adolescents through involvement of the cervical lymph nodes, presenting a massive bilateral lymphadenopathy, the characteristic aspect most described in the literature. Fever, leukocytois, and high erythrocyte sedimentation rates have een reported. Although the presenting symptoms are comparable to an infection, its etiology remains unknown. A link to immunologic disorders has een suggested, yet there has been no confirmation of specific mechanism to support this claim. Extranodal manifestations of the disease occur in up to 43% of patients, with 75% presenting manifestations
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