Abstract
MicroRNAs (miRNAs) are endogenous non-coding small RNAs of approximately 22 nucleotides in length. miRNAs repress expression of target genes at the posttranscription level. Biological relevance of miRNAs have been investigated in physiological and pathological conditions, revealing their involvement in fine tuning of the biological events, such as cell proliferation, differentiation and cell death. In 2008, miR-146a and miR-155 were reported to be involved in the pathology of rheumatoid arthritis. Subsequently, expression and function of other miRNAs in rheumatoid arthritis have been reported. These reports suggest that miRNAs could be novel candidates for the therapeutic target or biomarker of rheumatoid arthritis. Further investigations are required to identify, characterize and modulate the key miRNA in the pathology of rheumatoid arthritis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
