Abstract
The diagnosis of acute appendicitis still remains an enigma for the surgeon. The Mean Platelet volume is known to be a marker determined from megakaryocytes during platelet production, which is associated with platelet function and activation.The mean platelet volume (MPV) decreases in acute inflammatory conditions like acute appendicitis due to increased consumption and sequestration of platelets in the vascular segments of inflamed bowel. In our study of 213 patients, the MPV was determined and was found to be low ( < 7.6fL) in 176 patients ( 82.6%) out of which 175 patients were having features of acute appendicitis on histopathology. Therefore in a patient with a provisional diagnosis of acute appendicitis, a low MPV (<7.6fL) can be taken into consideration along with total leucocyte count with suspected acute appendicitis.
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