Abstract
Role of ischemia-reperfusion in oxidative stress-mediated injury during kidney transplantation
Highlights
Worldwide, chronic kidney disease (CKD) is a highly prevalent pathology [1]
According to estimates from the 2015 Global Burden of Disease study, approximately 1.2 million deaths are attributable to CKD [6], making it plausible to state that kidney disease could contribute more mortality than the main four target diseases defined by the WHO Global Action Plan for the Prevention and Control of Non-Communicable Diseases [7]
The results reported a significant enhance of renal function biomarkers and antioxidant enzyme function (e.g. CAT, superoxide dismutase (SOD) and GSH-Px) in the supplemented group compared to the ischaemia-reperfusion group [34]
Summary
Role of ischemia-reperfusion in oxidative stress-mediated injury during kidney transplantation.
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