Gene | VOL. 823
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Role of genomics in combating COVID-19 pandemic.

Publication Date May 20, 2022

Abstract

The coronavirus disease 2019 (COVID-19) quickly swept over the world, becoming one of the most devastating outbreaks in human history. Being the first pandemic in the post-genomic era, advancements in genomics contributed significantly to scientific understanding and public health response to COVID-19. Genomic technologies have been employed by researchers all over the world to better understand the biology of SARS-CoV-2 and its origin, genomic diversity, and evolution. Worldwide genomic resources have greatly aided in the investigation of the COVID-19 pandemic. The pandemic has ushered in a new era of genomic surveillance, wherein scientists are tracking the changes of the SARS-CoV-2 genome in real-time at the international and national levels. Availability of genomic and proteomic information enables the rapid development of molecular diagnostics and therapeutics. The advent of high-throughput sequencing and genome editing technologies led to the development of modern vaccines. We briefly discuss the impact of genomics in the ongoing COVID-19 pandemic in this review.

Concepts
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Coronavirus Disease 2019 Pandemic
Coronavirus Disease 2019
Post-genomic Era
High-throughput Genome Editing
Genomic Diversity
Genome Editing
Human History
National Levels
High-throughput Sequencing Technologies
Molecular Therapeutics

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