Abstract
Background: Granulomatous inflammation is a common diagnosis given in fine-needle aspirationcytology (FNAC) and it is a type of chronic inflammation in which tissue reaction appears followingcell injury. Aims: To assess the usefulness of the cytological study in the diagnosis of granulomatouslesions. Materials and Methods: An observational study is done based on cytomorphologicalevaluation of 156 cases of granulomatous inflammation diagnosed at the Department of Pathology,in Surat Municipal Institute of Medical Education & Research over 18 months from February 2018 toJuly 2019. Results: Out of the total of 156 cases of granulomatous inflammation, tuberculosis wasthe most common finding in 111 cases (71.15%), followed by fungal infection (05 cases). The maleto female ratio was 1.0 to 1.4. The most commonly affected age group was 21 to 30 years.Conclusions: All the cases of granulomatous inflammations are analysed for definitive diagnosis toprovide early and proper treatment of underlying diseases, malignancies or lymphoma.
Highlights
Materials and methodsGranulomatous inflammation is a distinctive form of chronic inflammation produced in response to various infectious, autoimmune, toxic, allergic, and neoplastic conditions. [1]
Granulomatous inflammation is a common diagnosis given in fine-needle aspiration cytology (FNAC) and it is a type of chronic inflammation in which tissue reaction appears following cell injury
Materials and Methods: An observational study is done based on cytomorphological evaluation of 156 cases of granulomatous inflammation diagnosed at the Department of Pathology, in Surat Municipal Institute of Medical Education & Research over 18 months from February 2018 to July 2019
Summary
Materials and methodsGranulomatous inflammation is a distinctive form of chronic inflammation produced in response to various infectious, autoimmune, toxic, allergic, and neoplastic conditions. [1]. Infectious causes most notably presenting with granuloma are tuberculosis and fungal infections. It is characterized by the formation of distinct granulomas composed of aggregates of epithelioid histiocytes, with a peripheral cuff of lymphocytes and plasma cells, and occasionally a necrotic centre. The commonly performed tests include examination of sputum for Acid Fast Bacilli, Cultures for Mycobacterium tuberculosis, Fine Needle Aspiration Cytology (FNAC), Biopsy, and PCR. Granulomatous inflammation is a common diagnosis given in fine-needle aspiration cytology (FNAC) and it is a type of chronic inflammation in which tissue reaction appears following cell injury. Results: Out of the total of 156 cases of granulomatous inflammation, tuberculosis was the most common finding in 111 cases (71.15%), followed by fungal infection (05 cases). Conclusions: All the cases of granulomatous inflammations are analysed for definitive diagnosis to provide early and proper treatment of underlying diseases, malignancies or lymphoma
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