Abstract
Production of antifungal compounds by Chaetomium globosum and the role in suppression of Pythium damping-off of sugarbeet were evaluated. Two metabolites with antifungal activity against Pythium ultimum, 2-(buta-1,3-dienyl)-3-hydroxy-4-(penta-1,3-dienyl)-tetrahydrofuran (BHT) and the epidithiadiketopiperazine, chaetomin, were isolated from liquid cultures of C. globosum. BHT was produced in 1% malt extract medium by six of eight tested C. globosum strains, whereas chaetomin was produced in 1% corn steep medium by five of nine tested strains (...)
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