Abstract

The Spanish government declared the lockdown on March 14th, 2020 to tackle the fast-spreading of COVID-19. As a consequence, the Balearic Islands remained almost fully isolated due to the closing of airports and ports, these isolation measures and the home-based confinement have led to a low prevalence of COVID-19 in this region. We propose a compartmental model for the spread of COVID-19 including five compartments (Susceptible, Exposed, Presymptomatic Infective, Diseased, and Recovered), and the mobility between municipalities. The model parameters are calibrated with the temporal series of confirmed cases provided by the Spanish Ministry of Health. After calibration, the proposed model captures the trend of the official confirmed cases before and after the lockdown. We show that the estimated number of cases depends strongly on the initial dates of the local outbreak onset and the number of imported cases before the lockdown. Our estimations indicate that the population has not reached the level of herd immunization necessary to prevent future outbreaks. While the low prevalence, in comparison to mainland Spain, has prevented the saturation of the health system, this low prevalence translates into low immunization rates, therefore facilitating the propagation of new outbreaks that could lead to secondary waves of COVID-19 in the region. These findings warn about scenarios regarding after-lockdown-policies and the risk of second outbreaks, emphasize the need for widespread testing, and could potentially be extrapolated to other insular and continental regions.

Highlights

  • The rapid propagation of the new COVID-19 pandemic requires timely responses, including the alignment of evidence generation by scientists and decision-making by policy stakeholders

  • For the scenario where the initial date was on Feb 7th, and a latent period of 2 days (Tlat = 2), an infective period of 4 days (Tinf = 4), and disease period of 12 days (Tdis = 12), the values of the infection probability leading to the best fit are β1 = 0.24, β2 = 0.12, β3 = 0.016, and β4 = 0.036 (Figure 2)

  • Assuming recovered individuals get immunity, to estimate whether the Balearic Islands have reached herd immunization, we explored the estimated number of infected cases under two immunization scenarios based on the date of the first infection (Figure 4A) and the number of imported cases before air and maritime transport lockdown (Figure 4B)

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Summary

Introduction

The rapid propagation of the new COVID-19 pandemic requires timely responses, including the alignment of evidence generation by scientists and decision-making by policy stakeholders. Risk of Secondary Infection Waves strategies to lockdown measures [1,2,3,4,5,6]. Recent studies have dealt with the possibility of a second-wave of COVID-19 after the retirement of lockdown and confinement measures in China [1, 2]. The value of restrictive social distancing measures has been largely proved since the first outbreak of the pandemic in European countries such as Italy [8]. The analysis of data from closed confinements such as sea cruises allows us to address some key questions regarding the risk of second waves in an environment without external perturbations [9, 10]. The study of the evolution of the pathogen in islands offers an opportunity to learn how the propagation occurs, and how the mobility restrictions are shaping the propagation in relatively isolated areas, either due to transport lockdowns implemented to contain COVID-19 dissemination or because of their geographical conditions

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