Risk factors of depressive and anxiety symptoms in patients with digestive organic disease

Abstract

Objective To explore the prevalence and possible risk factors of depressive/anxious symptoms of patients with digestive disease. Methods Totally 245 patients with digestive diseases were recruited consecutively.Face-to-face interview and the hospital anxiety and depression scale(HADS), self-rating anxiety scale(SAS) and self-rating depression scale(SDS) were employed to collect the clinical data.The non-condition logistic regression was performed to analyze the data. Results The prevalence of depression and anxiety in patients with organic diseases in digestive system was 36.3%.Among them, the higher incidence of depression and anxiety symptoms were digestive system tumors, peptic ulcer, acute pancreatitis and cirrhosis.The educational degree was correlated with simple depression, pure anxiety, depression complicated with anxiety (χ2=8.781, P=0.013; χ2=7.976, P=0.018; χ2=15.807, P=0.003), the degree of high school or above was a protective factor, the OR values were 0.347, 0.373, 0.301.The gender was also correlated with depression, anxiety, depression complicated with anxiety (χ2=4.343, P=0.031; χ2=1.056, P=0.017; χ2=2.382, P=0.03), female was the risk factor of mental illness, the OR values were 2.72, 2.438, 2.671.The age was correlated with depression, depression complicated with anxiety (χ2=9.872, P=0.002; χ2=15.710, P=0.031), the age of over 40 years old was the risk factor of mental illness, the OR values were 5.137, 5.731.The occupation was correlated with depression(χ2=6.017, P=0.017), the non-physical labor was the risk factors of depression, the OR value was 2.752. Conclusion There is a higher prevalence of depression and anxious symptoms in patients with digestive organic diseases.Female, senior high school or lower, older than 40 years, and non-manual work are the risk factors of these symptoms. Key words: Anxiety; Depression; Digestive system diseases; Factor analysis, statistical