Abstract
The Journal is the primary organ of Continuing Paediatric Medical Education in Sri Lanka. The journal also has a website. Free full text access is available for all readers.The Sri Lanka Journal of Child Health is now indexed in SciVerse Scopus (Source Record ID 19900193609), Index Medicus for South-East Asia Region (IMSEAR), CABI (Centre for Agriculture and Bioscience International Global Health Database), DOAJ and is available in Google, as well as Google Scholar.The policies of the journal are modelled on the Committee on Publication Ethics (COPE) Guidelines on Principles of Transparency and Best Practice in Scholarly Publishing. Sri Lanka Journal of Child Health is recognised by the International Committee of Medical Journal Editors (ICMJE) as a publication following the ICMJE Recommendations.
Highlights
Urinary tract infection (UTI) is one of the predominant causes of febrile illness in children with demanding antimicrobial therapy and it is a common nosocomial infection[1,2]
Extended Spectrum Beta Lactamase (ESBL) UTI was common in the age group 2 months to 2 years and was more common in males
Higher rates of pyelonephritis, voiding dysfunction, renal abnormalities and vesico-ureteric reflux (VUR) were detected in ultrasonogram of patients with ESBL UTI
Summary
Urinary tract infection (UTI) is one of the predominant causes of febrile illness in children with demanding antimicrobial therapy and it is a common nosocomial infection[1,2]. 8% of females and 2% of males, experience at least one incident of UTI by seven years of age, and recurrence occurs in up to 30% during a year[1]. UTI has a male to female ratio of 3-5:1. Worldwide prevalence of Extended Spectrum Beta Lactamase (ESBL) infections has been steadily increasing with predominantly Escherichia coli and Klebsiella uropathogens and they were described as a pandemic in most regions[1]. Beta lactamases produced by bacteria protect against lethal effects of penicillins, cephalosporins and monobactams on their cell wall synthesis. Therapy of ESBL UTI is more difficult as these strains are increasingly resistant to other non-Beta lactam antibiotics, promoting increased usage of expensive broad spectrum antibiotics like carbapenems[5]
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