Abstract
I herein present a unique statement, not focusing on the specific area but present an integrated viewpoint through...
Highlights
I present a unique statement, not focusing on the specific area but present an integrated viewpoint through MRI epidemiology to animal experiment
It is well known that Alzheimer disease (AD) and vascular dementia (VaD) are two major dementing diseases [1,2], and the clinical features are different; grossly, AD shows disintegrated emotion and cognitive function, and VaD shows apathy
The diagnosis is VaD, and her amnesia was explained by the disturbed Papez circuit involving anteroventral nucleus (AN) as illustrated in the right part of (Figure 1)
Summary
I present a unique statement, not focusing on the specific area but present an integrated viewpoint through MRI epidemiology to animal experiment. The aim is to provide a perspective for better understanding clinical features of Alzheimer disease (AD) and vascular dementia (VaD). It is well known that AD and VaD are two major dementing diseases [1,2], and the clinical features are different; grossly, AD shows disintegrated emotion and cognitive function, and VaD shows apathy. I will present two typical VaD cases
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