Abstract
Two rhenium isotopes (186Re and 188Re) are of interest for nuclear medicine. The multiplicity of oxidation states and varying coordination chemistry of rhenium provide opportunities for the synthesis of various bioconjugates, including those based on nanosized carriers (liposomes, dendrimers, and inorganic nanoparticles). This review analyzes nuclear reactions that lead to the formation of rhenium isotopes and methods of their isolation from targets, as well as different variants of the application of rhenium in nuclear medicine.
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